The vampire brothers Damon and Stefan Salvatore, eternal adolescents, having been leading 'normal' lives, hiding their bloodthirsty condition, for centuries, moving on before their non-aging is noticed. They are back in the Virginia town where they became vampires. Stefan is noble, denying himself blood to avoid killing, and tries to control his evil brother Damon. Stefan falls in love with schoolgirl Elena, whose best friend is a witch, like her grandma.
Meet the fabulously dysfunctional Gallagher family. Dad's a drunk, Mom split long ago, eldest daughter Fiona tries to hold the family together. Eldest son Philip (Lip) trades his physics tutoring skills for sexual favors from neighborhood girls. Middle son Ian is gay. Youngest daughter Debbie is stealing money from her UNICEF collection. Ten-year-old Carl is a budding sociopath and an arsonist, and toddler Liam is - well, he might actually be black, but nobody has a clue how.